SM22α Modulates Vascular Smooth Muscle Cell Phenotype During Atherogenesis

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SM22 Modulates Vascular Smooth Muscle Cell Phenotype During Atherogenesis

The function of cytoskeletal proteins in the modulation of vascular smooth muscle cell (SMC) phenotype during vascular disease is poorly understood. In this report, we used a combination of gene targeting and Cre/loxmediated cell fate mapping in mice to investigate the role of SM22 , an SMC-specific cytoskeletal protein of unknown function, in the development of atherosclerosis. In hypercholest...

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ژورنال

عنوان ژورنال: Circulation Research

سال: 2004

ISSN: 0009-7330,1524-4571

DOI: 10.1161/01.res.0000126417.38728.f6